Visitors easily chase down 221 with Mohammad Hafeez contributing 72 after a superb effort by the bowlers restricted the hosts.
Pakistan fall short by 92 runs with James Faulkner picking up four wickets after wicket-keeper Wade had helped hosts to a competitive total of 268/9.
Writing in his latest blog for PakPassion.net, Aamir Sohail analyses the causes of Pakistan's disappointing performance in the recently concluded Test series against Australia and also discusses the futures of Younis Khan and Misbah-ul-Haq.
Sarfraz Ahmed was the only one to play an innings of note, finishing on 72* as visitors were bowled out for 244.
Visitors finish day at 55/1 after Australia went at a stunning run-rate of 7.5 to make 241/2d in the second innings.
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Visitors finish rain-hit day at 271/8 with the veteran unbeaten on 136, 267 runs behind Australia's first-innings total.
Pakistan finish day at 126/2, 412 runs behind hosts' first-innings total with both batsmen having hit unbeaten fifties.
Warner hit a quick-fire 113 with Renshaw finishing on 167* as Australia end Day 1 at a commanding 365/3.